TAP

THE ANSWER PROJECT

AI-Native Drug Discovery

Building intelligent networks that connect global expertise, computational models, and experimental capabilities. Our platform integrates dynamic discovery flows, continuous learning loops, and strategic deployment to accelerate therapeutic development.

Distributed innovation networks + multi-objective optimization = breakthrough therapeutics

Technical Overview

AI-Native Architecture

Our platform is built from the ground up as an AI-native system, creating intelligent networks that connect global expertise, computational models, and experimental capabilities. This reveals optimal collaborations and breakthrough opportunities that traditional siloed approaches cannot identify.

Meta-Learning System

Each collaboration teaches the network how to form better connections, transforming drug discovery into a continuously improving, distributed intelligence. Our system doesn't just learn about molecules—it learns how to optimize the innovation process itself.

Network Effects

Our network-based approach unlocks powerful effects where each new participant makes the entire system exponentially more capable at discovering breakthrough medicines. The network grows smarter with every interaction.

Core Technologies

Advanced AI Models

Our platform leverages state-of-the-art AI architectures:

  • Transformer architectures for molecular sequence analysis
  • Convolutional Neural Networks (CNN) for structural imaging
  • Bayesian optimization for experimental design
  • Multi-modal learning across chemical and biological spaces

System Architecture

Built on modern architectural principles:

  • Event-driven architecture for real-time processing
  • Distributed computing for model training
  • Scalable microservices deployment
  • High-throughput data pipelines

Integration Capabilities

Comprehensive integration across:

  • Computer vision for experimental analysis
  • Automated laboratory systems
  • Molecular modeling platforms
  • Clinical data systems

Scientific Foundation

Network Foundation

Distributed Network

We coordinate a distributed network of world-class talent, cutting-edge technologies, and leading institutions. Our in-house capabilities are amplified through strategic partnerships with:

  • Academic research institutions
  • Contract research organizations
  • Clinical research centers
  • Industry partners

Deep Learning Infrastructure

Built from the ground up with AI/ML at the core. Our computational infrastructure spans across our network, enabling distributed processing and model deployment.

Network Orchestration

Seamless coordination of distributed capabilities through our orchestration platform, ensuring efficient resource allocation and communication across all network nodes.

Discovery Flow

Portfolio Strategy

We pursue portfolios by indication through focused "Answer Projections" - TAP Neuro, TAP Oncology, and others. These are agile sprinter groups formed to concentrate efforts around specific initiatives. We dynamically create new Answer Projections as opportunities emerge, enabling rapid deployment of our platform across diverse therapeutic areas.

Accelerated Timeline

Parallel processing across our network accelerates discovery timelines. Our learn-fast/kill-fast approach enables rapid decision-making and program advancement.

Development Pipeline

Continuous flow from target discovery through preclinical and clinical development, with computational predictions guiding each stage.

Empirical Loop

AI/ML Feedback

Every experimental result feeds back into our AI models, creating a continuous learning loop that improves predictive accuracy across our entire network.

Validation Cycle

Rapid empirical validation of computational predictions, with results immediately informing model refinement and next-round predictions.

Precision Optimization

Iterative refinement of both computational models and experimental approaches, continuously improving the accuracy and efficiency of our discovery process.

External Deployment

Strategic Partnerships

Active engagement with pharmaceutical partners, leveraging our platform to accelerate and de-risk their development programs.

Clinical Translation

Seamless transition from discovery to clinical development through our network of clinical research organizations and medical institutions.

Market Interface

Strategic commercialization through established industry networks, ensuring successful market access and therapeutic deployment.

Platform

Distributed Infrastructure

Our platform orchestrates a global network of computational and experimental capabilities, enabling seamless integration of AI-driven predictions with rapid empirical validation.

Continuous Learning

Every experimental result feeds back into our AI models, creating a continuous learning loop that improves predictive accuracy across the entire network.

Strategic Deployment

Seamless transition from discovery to development through our network of clinical research organizations and industry partners.

Our Team

Andrew Francis

Founder • Distributed Innovation • Entrepreneur, Impact Investor

Chan Hariyan, PharmD/MBA/MPH

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Special Assistant to the President, Biological Threats • Managing Director/Partner, BCG, PwC • Operation Warp Speed architect

Henk de Jong

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Corporate and Technology Strategy • Entrepreneur, Co-Founder ValueAI Institute • Investor, Venture Partner

John Baldoni, PhD

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Senior Pharma Leadership • AI-driven Drug Discovery, Portfolio • Platform Technology and Science, GSK

John Santerre, PhD

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Machine Learning, Deep Learning • AI Researcher/Instructor, Berkeley, NASA • Founder, Silicon Valley Bank AI Lab

Rebecca Kurnat, MS

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Head of Operations, SaponiQx • Novavax Vaccine Lead, US Government Operation Warp Speed • Technology Selection and Clinical Evaluation, Department of Defense

Christopher Bun, PhD

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Machine Learning, Computational Biology, Cancer Genomics • CSO / CTO, Cancer IQ

Joe Camardo, MD

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Medical Strategy • CMO, ADC Therapeutics • SVP, Celgene, Pfizer, Wyeth

Amar Sahay, PhD

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Neuroscience, Brain Plasticity • Professor, Harvard Medical School • Massachusetts General Hospital, BROAD Institute

Grant Bourzikas, MS

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Chief Security Officer, Cloudflare • CISO, McAfee, HSBC, Silicon Valley Bank

Robin Prince, PhD

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DNA Encoded Libraries • Informatics & Molecular Biology, Dice Therapeutics

Douglas Beshore, PhD

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Medicinal Chemist • Director, Exelixis • Principal Scientist, Merck

Mike Yassa, PhD

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Neurology, Behavior, Psychiatry • Professor, UC Irvine, Neurobiology • Chief Scientific Officer, Signa Tx

Sara Burke, PhD

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Neuroscience, Cognitive Aging, Memory • Professor, University of Florida

Steven Spear, PhD/MEM

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Management Systems • High Performance Organization • Senior Lecturer, MIT Sloan

Elden Lainez

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Lab Operations • Director of Facilities, Moderna • Operations, GSK, AstraZeneca

Ashley Lim, MBA

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Life Sciences Strategy & Business Operations • Supply Chain, Project Management • Boston Consulting Group

Alph Bingham, PhD

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Senior Pharma Leadership • Collaborative Drug Discovery, InnoCentive • R&D Executive, Eli Lilly

Andrew Anderson, MBA

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Life Sciences Software • VP Innovation, ACD labs

Timur Yusufzai, PhD

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Life Sciences Entrepreneur • Co-founder, Episode 1, MOMA • EIR, Third Rock Ventures • Faculty, Harvard Medical School

Contact

TAP engages with partners by referral.